"Lifedance: The area dividing the brain and the soul is affected in many ways by experience--- some lose all mind and become soul: insane. Some lose all soul and become mind: intellectual. Some lose both and come: accepted.
Drapetomania (Came from the slave days, and was considered a medical disease which needed curing if a slave was wanting to escape. So, metaphorically speaking, this word can be used as a noun if you feel trapped and ache for escape.