Pest Control 1. Keep roaches, waterbugs, and ants away by sprinkling a combination of equal parts all-natural borax and sugar. 2. Keep the mice out by sprinkling borax on the floor along the wall. 3. Get rid of bed bugs by sprinkling borax on your mattress. Let it sit and vacuum it up. 4. Kill fleas by sprinkling borax on your carpet. Leave it for an hour and vacuum it up thoroughly.