DIONYSIOS TRYFONAS

DIONYSIOS TRYFONAS

DIONYSIOS TRYFONAS
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Multiple myeloma is a cancer of your plasma cells, a type of white blood cell present in your bone marrow. Plasma cells normally make proteins calledantibodies to help you fight infections.    In multiple myeloma, a group of plasma cells (myeloma cells) becomes cancerous and multiplies, raising the number of plasma cells to a higher than normal level. Since these cells normally make proteins (antibodies), the level of abnormal proteins in your blood also may go up.

Multiple myeloma is a cancer of your plasma cells, a type of white blood cell present in your bone marrow. Plasma cells normally make proteins calledantibodies to help you fight infections. In multiple myeloma, a group of plasma cells (myeloma cells) becomes cancerous and multiplies, raising the number of plasma cells to a higher than normal level. Since these cells normally make proteins (antibodies), the level of abnormal proteins in your blood also may go up.

EDTA dependent pseudothrombocytopenia

Aim of the study was to clarify the mechanisms involved in the development of EDTA dependent pseudothrombocytopenia, particularly the platel.

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Myeloblast with three nucleoli, and nucleated RBC

Myeloblast with three nucleoli, and nucleated RBC

[ACUTE MYELOGENOUS LEUKEMIA, M0, BLOOD]. A myeloblast of an AML-M0 is compared to a medium-sized normal lymphocyte. Note the presence of only very scant cytoplasm in a blast and finer evenly-distributed chromatin in comparison to a lymphocyte. The high nuclear to cytoplasmic ration (N/C ratio) is a common albeit not a required feature of blasts. The single defining morphologic feature of a blast is it’s finely distributed nuclear chromatin.

[ACUTE MYELOGENOUS LEUKEMIA, M0, BLOOD]. A myeloblast of an AML-M0 is compared to a medium-sized normal lymphocyte. Note the presence of only very scant cytoplasm in a blast and finer evenly-distributed chromatin in comparison to a lymphocyte. The high nuclear to cytoplasmic ration (N/C ratio) is a common albeit not a required feature of blasts. The single defining morphologic feature of a blast is it’s finely distributed nuclear chromatin.

Acute Myeloid Leukemia - Auer Rods

cytoplasm of myeloblasts contains auer rods (distinctive needle-like granules); Particularly numerous in the ME FAB subtype.

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