How a healthy microbiome could supercharge the body's natural cancer-fighting cells
Adding to our understanding of how the bacteria living in and on the human body is a new discovery by researchers in Melbourne, who have described how a healthy microbiome can boost the activity of killer immune cells that are vital to fighting off infections and cancer.
Dietary restriction (DR) slows down tumor growth by increasing tumor immunosurveillance. Rubio-Patiño et al. show that a moderate reduction in dietary protein intake, rather than carbohydrate reduction, without overall calorie changes, activates the IRE1α/RIG1 pathway in tumor cells resulting in an anticancer immune response in mice.