Breakthrough in treating mitochondrial eye disease including dominant optic atrophy, a hereditary eye disease which causes loss of vision. Reduction of Inner Retinal Thickness in Patients with Autosomal Dominant Optic Atrophy Associated with Mutations
Horner syndrome results from an interruption of the sympathetic nerve supply to the eye and is characterized by the classic triad of miosis (ie, constricted pupil), partial ptosis, and loss of hemifacial sweating (ie, anhidrosis).
The coca-cola bottle sign refers to the appearance of the muscles of the orbit in thyroid eye disease. The belly of the muscle enlarges with sparing of the tendinous insertion, giving the appearance of the traditional coca-cola bottle. The enlargement of the muscles follows the I'M SLOW format. The nature of the enlargement is important as in one of the chief differentials, orbital pseudotumour, the tendinous insertion is also involved and enlarged, unlike in thyroid eye disease.
This is a picture of choroidal nevus which has a paler color and less distinct edge than CHRPE: CHRPE is darker than choroidal nevus (typically) nevus is brownish whereas CHRPE is black, Visual field: CHRPE gives absolute scotoma whereas choroidal naevus does not affect the field, Malignant potential: CHRPE has no malignant potential whereas nevus, may transform into malignant melanoma. Red Free Filter: Green light is absorbed by RPE & structures deeper than RPE will be invisible. (I.e…
Foster Kennedy Syndrome: Unilateral Optic atrophy with contralateral papilledema and anosmia, usually due to a frontal lobe tumor or a meningioma. is thought to be present in to of intracranial masses.
angioid streaks 50% are associated with a systemic condition and 50% are idiopathic. Mnemonic: PEPSI -Pseudoxanthoma elasticum -Ehlers-Danlos syndrome (Fibrodysplasia hyperplastica) -Paget's disease (Increased bone productino and destruction) -Sickle Cell -Idiopathic